It is used regularly to write academic papers (examples here <https://www.texmacs.org/joris/main/publs.html>) and thesis, examples here: <https://github.com/texmacs/tm-forge/tree/main/examples/these...> and here <https://texmacs.github.io/notes/docs/example-documents.html>. It is used to write lecture notes and to deliver lectures online (e.g. here https://www.youtube.com/playlist?list=PLjXdYclFpynDi7EYP95Ep...). It can be used to produce full static website (e.g. here <https://mgubi.github.io/docs/main.html>, here <https://www.texmacs.org/tmweb/home/welcome.en.html> and here <https://texmacs.github.io/notes/docs/main.html>). There are not many users, but it is a working software with regular updates, since ~2000. Who compare it to LaTeX or Typst miss the point that it is a software designed to render writing a lot of mathematics easier and more importantly to not loose focus in irrelevant details. It has a visual macro system (see e.g. <https://x.com/gnu_texmacs/status/1251554336842407938>), something I haven't seen elsewhere, in production software. It is a structure editor, and an exploration of the design space in scientific editors. A field which lacks innovation and creativity.

GNU Texmacs